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Derek Lowe's recent post on plasticizer impurities brings to mind a good question: how do you know if you've isolated a plasticizer (from, say, Tygon tubing) rather than your desired product? What are common plasticizer impurities? Finally, what are the best ways of avoiding said impurities?

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2 Answers

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I assume you mean phthalate and NMR spectra?. Usually you get a few signals in the aromatic region of the NMR and a load of strong signals in the aliphatic region. To avoid these impurities, do not use this material in contact with organic solvents.

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Always, always, always run a control.

Unless labeled as unplasticizd PVC, PVC will have plasticisers. And heat stabilizers. And lubricants. And maybe UV absorbers and pigments and... The long and short of it, PVC is loaded with endless additives. And even the UPVC might still have some plasticizers in it.

If it is important, simply avoid working with it. There are plenty of other alternatives, although every plastic will have some additives in it, most often thermal stabilizers.

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