One of the most useful instruments I ever worked with was a chromatography system from a company called Isco (now Teledyne Isco). They used to make a simpler version of their current systems that consisted of a retro mechanical strip-chart recorder, a fraction collector, and pump/control capable of doing gradients. It used disposable silica cartridges, so there was never any column packing. It eliminated the need to be present while doing routine purifications (flash chromatograph), a big productivity boost.
What made this instrument great was its low cost and simplicity. But it was on the bulky side and still cost too much for the average employee to buy on their own. I often wished the manufacturer would offer a smaller, cheaper version, but instead they decided to go the other way (this may have changed, I'm not sure).
If you could convince an instrument maker to create one product to make your life in the lab easier, what would it be?
